mouse fap Search Results


mouse igg1 isotype control  (Bio-Techne corporation)
96
Bio-Techne corporation mouse igg1 isotype control
Mouse Igg1 Isotype Control, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+fap/bio-techne+corporation___mab002?v=Bio-Techne+corporation
Average 96 stars, based on 1 article reviews
mouse igg1 isotype control - by Bioz Stars, 2026-07
96/100 stars
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fap  (R&D Systems)
93
R&D Systems fap
A Schematic diagram of fibrosis model establishment and treatment strategy in young or aged mice. B , C Young mouse BW changes ( B ) and survival curve ( C ) of control and BLM groups treated with IgG/ β LNP-FAPCAR 2.2, CD5/ β LNP-FAPCAR 2.2 (10 μg) and saline ( n = 10). The survival rate was analyzed using the log-rank (Mantel-Cox) test. D Lung coefficients (lung weight (mg)/BW (g)) ( n = 5,5,10,10,10,7). E tdTomato reporter gene expressed in T cells of spleen and lung at 24 h after the second CD5/ β LNP-FAPCAR 2.2 injection (Scar bar: 10 μm). F Flow cytometry plots for FAPCAR expression in CD3 + pulmonary T cells of BLM+Saline and CD5/ β LNP-FAPCAR 2.2 treatment groups and the ratio of FAPCAR expression to CD3 + pulmonary T cells ( n = 4). G Flow cytometry analysis of <t>FAP</t> <t>+</t> <t>Pdgfra</t> + fibroblasts in BLM+Saline and CD5/ β LNP-FAPCAR 2.2 treatment groups, ratio of FAP + Pdgfra + fibroblasts to all lung cells, and ratio of Pdgfra + fibroblasts (both FAP + and FAP — ) to all lung cells ( n = 4). H , I Representative micro-CT images and mean HU density ( H ), and lung air volume (mm 3 ) ( I ) computed according to CT results at postoperative 28 days ( n = 4,4,7,7,7,7). J Digital photos of lung tissue. ‘n’ means independent biological replications. The values are the means ± SDs. * P < 0.05. P -value determined by one-way ANOVA followed by Tukey’s multiple comparisons test ( D , F , H , I ) and two tailed unpaired Student’s t -test ( G ). (BW: body weight; HU: Hounsfield unit). Source data are provided as a Source Data file. Created in BioRender ( A , B ) .
Fap, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+fap/pmc12012202-388-29-31?v=R%26D+Systems
Average 93 stars, based on 1 article reviews
fap - by Bioz Stars, 2026-07
93/100 stars
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recombinant fap  (R&D Systems)
94
R&D Systems recombinant fap
A Schematic diagram of fibrosis model establishment and treatment strategy in young or aged mice. B , C Young mouse BW changes ( B ) and survival curve ( C ) of control and BLM groups treated with IgG/ β LNP-FAPCAR 2.2, CD5/ β LNP-FAPCAR 2.2 (10 μg) and saline ( n = 10). The survival rate was analyzed using the log-rank (Mantel-Cox) test. D Lung coefficients (lung weight (mg)/BW (g)) ( n = 5,5,10,10,10,7). E tdTomato reporter gene expressed in T cells of spleen and lung at 24 h after the second CD5/ β LNP-FAPCAR 2.2 injection (Scar bar: 10 μm). F Flow cytometry plots for FAPCAR expression in CD3 + pulmonary T cells of BLM+Saline and CD5/ β LNP-FAPCAR 2.2 treatment groups and the ratio of FAPCAR expression to CD3 + pulmonary T cells ( n = 4). G Flow cytometry analysis of <t>FAP</t> <t>+</t> <t>Pdgfra</t> + fibroblasts in BLM+Saline and CD5/ β LNP-FAPCAR 2.2 treatment groups, ratio of FAP + Pdgfra + fibroblasts to all lung cells, and ratio of Pdgfra + fibroblasts (both FAP + and FAP — ) to all lung cells ( n = 4). H , I Representative micro-CT images and mean HU density ( H ), and lung air volume (mm 3 ) ( I ) computed according to CT results at postoperative 28 days ( n = 4,4,7,7,7,7). J Digital photos of lung tissue. ‘n’ means independent biological replications. The values are the means ± SDs. * P < 0.05. P -value determined by one-way ANOVA followed by Tukey’s multiple comparisons test ( D , F , H , I ) and two tailed unpaired Student’s t -test ( G ). (BW: body weight; HU: Hounsfield unit). Source data are provided as a Source Data file. Created in BioRender ( A , B ) .
Recombinant Fap, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+fap/10__1042_slash_bj20151085-82-22-24?v=R%26D+Systems
Average 94 stars, based on 1 article reviews
recombinant fap - by Bioz Stars, 2026-07
94/100 stars
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usingduosetmousefap  (R&D Systems)
93
R&D Systems usingduosetmousefap
A Schematic diagram of fibrosis model establishment and treatment strategy in young or aged mice. B , C Young mouse BW changes ( B ) and survival curve ( C ) of control and BLM groups treated with IgG/ β LNP-FAPCAR 2.2, CD5/ β LNP-FAPCAR 2.2 (10 μg) and saline ( n = 10). The survival rate was analyzed using the log-rank (Mantel-Cox) test. D Lung coefficients (lung weight (mg)/BW (g)) ( n = 5,5,10,10,10,7). E tdTomato reporter gene expressed in T cells of spleen and lung at 24 h after the second CD5/ β LNP-FAPCAR 2.2 injection (Scar bar: 10 μm). F Flow cytometry plots for FAPCAR expression in CD3 + pulmonary T cells of BLM+Saline and CD5/ β LNP-FAPCAR 2.2 treatment groups and the ratio of FAPCAR expression to CD3 + pulmonary T cells ( n = 4). G Flow cytometry analysis of <t>FAP</t> <t>+</t> <t>Pdgfra</t> + fibroblasts in BLM+Saline and CD5/ β LNP-FAPCAR 2.2 treatment groups, ratio of FAP + Pdgfra + fibroblasts to all lung cells, and ratio of Pdgfra + fibroblasts (both FAP + and FAP — ) to all lung cells ( n = 4). H , I Representative micro-CT images and mean HU density ( H ), and lung air volume (mm 3 ) ( I ) computed according to CT results at postoperative 28 days ( n = 4,4,7,7,7,7). J Digital photos of lung tissue. ‘n’ means independent biological replications. The values are the means ± SDs. * P < 0.05. P -value determined by one-way ANOVA followed by Tukey’s multiple comparisons test ( D , F , H , I ) and two tailed unpaired Student’s t -test ( G ). (BW: body weight; HU: Hounsfield unit). Source data are provided as a Source Data file. Created in BioRender ( A , B ) .
Usingduosetmousefap, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+fap/pm41266527-486-15-16?v=R%26D+Systems
Average 93 stars, based on 1 article reviews
usingduosetmousefap - by Bioz Stars, 2026-07
93/100 stars
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fibroblast activation protein α  (R&D Systems)
94
R&D Systems fibroblast activation protein α
A Schematic diagram of fibrosis model establishment and treatment strategy in young or aged mice. B , C Young mouse BW changes ( B ) and survival curve ( C ) of control and BLM groups treated with IgG/ β LNP-FAPCAR 2.2, CD5/ β LNP-FAPCAR 2.2 (10 μg) and saline ( n = 10). The survival rate was analyzed using the log-rank (Mantel-Cox) test. D Lung coefficients (lung weight (mg)/BW (g)) ( n = 5,5,10,10,10,7). E tdTomato reporter gene expressed in T cells of spleen and lung at 24 h after the second CD5/ β LNP-FAPCAR 2.2 injection (Scar bar: 10 μm). F Flow cytometry plots for FAPCAR expression in CD3 + pulmonary T cells of BLM+Saline and CD5/ β LNP-FAPCAR 2.2 treatment groups and the ratio of FAPCAR expression to CD3 + pulmonary T cells ( n = 4). G Flow cytometry analysis of <t>FAP</t> <t>+</t> <t>Pdgfra</t> + fibroblasts in BLM+Saline and CD5/ β LNP-FAPCAR 2.2 treatment groups, ratio of FAP + Pdgfra + fibroblasts to all lung cells, and ratio of Pdgfra + fibroblasts (both FAP + and FAP — ) to all lung cells ( n = 4). H , I Representative micro-CT images and mean HU density ( H ), and lung air volume (mm 3 ) ( I ) computed according to CT results at postoperative 28 days ( n = 4,4,7,7,7,7). J Digital photos of lung tissue. ‘n’ means independent biological replications. The values are the means ± SDs. * P < 0.05. P -value determined by one-way ANOVA followed by Tukey’s multiple comparisons test ( D , F , H , I ) and two tailed unpaired Student’s t -test ( G ). (BW: body weight; HU: Hounsfield unit). Source data are provided as a Source Data file. Created in BioRender ( A , B ) .
Fibroblast Activation Protein α, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+fap/pmc07201668-87-40-45?v=R%26D+Systems
Average 94 stars, based on 1 article reviews
fibroblast activation protein α - by Bioz Stars, 2026-07
94/100 stars
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anti α sma  (R&D Systems)
94
R&D Systems anti α sma
A Schematic diagram of fibrosis model establishment and treatment strategy in young or aged mice. B , C Young mouse BW changes ( B ) and survival curve ( C ) of control and BLM groups treated with IgG/ β LNP-FAPCAR 2.2, CD5/ β LNP-FAPCAR 2.2 (10 μg) and saline ( n = 10). The survival rate was analyzed using the log-rank (Mantel-Cox) test. D Lung coefficients (lung weight (mg)/BW (g)) ( n = 5,5,10,10,10,7). E tdTomato reporter gene expressed in T cells of spleen and lung at 24 h after the second CD5/ β LNP-FAPCAR 2.2 injection (Scar bar: 10 μm). F Flow cytometry plots for FAPCAR expression in CD3 + pulmonary T cells of BLM+Saline and CD5/ β LNP-FAPCAR 2.2 treatment groups and the ratio of FAPCAR expression to CD3 + pulmonary T cells ( n = 4). G Flow cytometry analysis of <t>FAP</t> <t>+</t> <t>Pdgfra</t> + fibroblasts in BLM+Saline and CD5/ β LNP-FAPCAR 2.2 treatment groups, ratio of FAP + Pdgfra + fibroblasts to all lung cells, and ratio of Pdgfra + fibroblasts (both FAP + and FAP — ) to all lung cells ( n = 4). H , I Representative micro-CT images and mean HU density ( H ), and lung air volume (mm 3 ) ( I ) computed according to CT results at postoperative 28 days ( n = 4,4,7,7,7,7). J Digital photos of lung tissue. ‘n’ means independent biological replications. The values are the means ± SDs. * P < 0.05. P -value determined by one-way ANOVA followed by Tukey’s multiple comparisons test ( D , F , H , I ) and two tailed unpaired Student’s t -test ( G ). (BW: body weight; HU: Hounsfield unit). Source data are provided as a Source Data file. Created in BioRender ( A , B ) .
Anti α Sma, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+fap/pm41570745-104-6-7?v=R%26D+Systems
Average 94 stars, based on 1 article reviews
anti α sma - by Bioz Stars, 2026-07
94/100 stars
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s8e fap r d systems fab9727r 100ug  (R&D Systems)
94
R&D Systems s8e fap r d systems fab9727r 100ug
A Schematic diagram of fibrosis model establishment and treatment strategy in young or aged mice. B , C Young mouse BW changes ( B ) and survival curve ( C ) of control and BLM groups treated with IgG/ β LNP-FAPCAR 2.2, CD5/ β LNP-FAPCAR 2.2 (10 μg) and saline ( n = 10). The survival rate was analyzed using the log-rank (Mantel-Cox) test. D Lung coefficients (lung weight (mg)/BW (g)) ( n = 5,5,10,10,10,7). E tdTomato reporter gene expressed in T cells of spleen and lung at 24 h after the second CD5/ β LNP-FAPCAR 2.2 injection (Scar bar: 10 μm). F Flow cytometry plots for FAPCAR expression in CD3 + pulmonary T cells of BLM+Saline and CD5/ β LNP-FAPCAR 2.2 treatment groups and the ratio of FAPCAR expression to CD3 + pulmonary T cells ( n = 4). G Flow cytometry analysis of <t>FAP</t> <t>+</t> <t>Pdgfra</t> + fibroblasts in BLM+Saline and CD5/ β LNP-FAPCAR 2.2 treatment groups, ratio of FAP + Pdgfra + fibroblasts to all lung cells, and ratio of Pdgfra + fibroblasts (both FAP + and FAP — ) to all lung cells ( n = 4). H , I Representative micro-CT images and mean HU density ( H ), and lung air volume (mm 3 ) ( I ) computed according to CT results at postoperative 28 days ( n = 4,4,7,7,7,7). J Digital photos of lung tissue. ‘n’ means independent biological replications. The values are the means ± SDs. * P < 0.05. P -value determined by one-way ANOVA followed by Tukey’s multiple comparisons test ( D , F , H , I ) and two tailed unpaired Student’s t -test ( G ). (BW: body weight; HU: Hounsfield unit). Source data are provided as a Source Data file. Created in BioRender ( A , B ) .
S8e Fap R D Systems Fab9727r 100ug, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+fap/pmc10352362__41467_2023_39953_MOESM1_ESM-77-116-118?v=R%26D+Systems
Average 94 stars, based on 1 article reviews
s8e fap r d systems fab9727r 100ug - by Bioz Stars, 2026-07
94/100 stars
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recombinant mouse fap protein  (R&D Systems)
93
R&D Systems recombinant mouse fap protein
A Schematic diagram of fibrosis model establishment and treatment strategy in young or aged mice. B , C Young mouse BW changes ( B ) and survival curve ( C ) of control and BLM groups treated with IgG/ β LNP-FAPCAR 2.2, CD5/ β LNP-FAPCAR 2.2 (10 μg) and saline ( n = 10). The survival rate was analyzed using the log-rank (Mantel-Cox) test. D Lung coefficients (lung weight (mg)/BW (g)) ( n = 5,5,10,10,10,7). E tdTomato reporter gene expressed in T cells of spleen and lung at 24 h after the second CD5/ β LNP-FAPCAR 2.2 injection (Scar bar: 10 μm). F Flow cytometry plots for FAPCAR expression in CD3 + pulmonary T cells of BLM+Saline and CD5/ β LNP-FAPCAR 2.2 treatment groups and the ratio of FAPCAR expression to CD3 + pulmonary T cells ( n = 4). G Flow cytometry analysis of <t>FAP</t> <t>+</t> <t>Pdgfra</t> + fibroblasts in BLM+Saline and CD5/ β LNP-FAPCAR 2.2 treatment groups, ratio of FAP + Pdgfra + fibroblasts to all lung cells, and ratio of Pdgfra + fibroblasts (both FAP + and FAP — ) to all lung cells ( n = 4). H , I Representative micro-CT images and mean HU density ( H ), and lung air volume (mm 3 ) ( I ) computed according to CT results at postoperative 28 days ( n = 4,4,7,7,7,7). J Digital photos of lung tissue. ‘n’ means independent biological replications. The values are the means ± SDs. * P < 0.05. P -value determined by one-way ANOVA followed by Tukey’s multiple comparisons test ( D , F , H , I ) and two tailed unpaired Student’s t -test ( G ). (BW: body weight; HU: Hounsfield unit). Source data are provided as a Source Data file. Created in BioRender ( A , B ) .
Recombinant Mouse Fap Protein, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+fap/pmc11692786__res___136___26___s004-58-9-15?v=R%26D+Systems
Average 93 stars, based on 1 article reviews
recombinant mouse fap protein - by Bioz Stars, 2026-07
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murine fap  (OriGene)
93
OriGene murine fap
A Schematic diagram of fibrosis model establishment and treatment strategy in young or aged mice. B , C Young mouse BW changes ( B ) and survival curve ( C ) of control and BLM groups treated with IgG/ β LNP-FAPCAR 2.2, CD5/ β LNP-FAPCAR 2.2 (10 μg) and saline ( n = 10). The survival rate was analyzed using the log-rank (Mantel-Cox) test. D Lung coefficients (lung weight (mg)/BW (g)) ( n = 5,5,10,10,10,7). E tdTomato reporter gene expressed in T cells of spleen and lung at 24 h after the second CD5/ β LNP-FAPCAR 2.2 injection (Scar bar: 10 μm). F Flow cytometry plots for FAPCAR expression in CD3 + pulmonary T cells of BLM+Saline and CD5/ β LNP-FAPCAR 2.2 treatment groups and the ratio of FAPCAR expression to CD3 + pulmonary T cells ( n = 4). G Flow cytometry analysis of <t>FAP</t> <t>+</t> <t>Pdgfra</t> + fibroblasts in BLM+Saline and CD5/ β LNP-FAPCAR 2.2 treatment groups, ratio of FAP + Pdgfra + fibroblasts to all lung cells, and ratio of Pdgfra + fibroblasts (both FAP + and FAP — ) to all lung cells ( n = 4). H , I Representative micro-CT images and mean HU density ( H ), and lung air volume (mm 3 ) ( I ) computed according to CT results at postoperative 28 days ( n = 4,4,7,7,7,7). J Digital photos of lung tissue. ‘n’ means independent biological replications. The values are the means ± SDs. * P < 0.05. P -value determined by one-way ANOVA followed by Tukey’s multiple comparisons test ( D , F , H , I ) and two tailed unpaired Student’s t -test ( G ). (BW: body weight; HU: Hounsfield unit). Source data are provided as a Source Data file. Created in BioRender ( A , B ) .
Murine Fap, supplied by OriGene, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+fap/pm39954291-40-5-10?v=OriGene
Average 93 stars, based on 1 article reviews
murine fap - by Bioz Stars, 2026-07
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mouse monoclonal anti-fap f19  (Becton Dickinson)
90
Becton Dickinson mouse monoclonal anti-fap f19
Immunohistochemistry in low-grade myofibroblastic sarcoma, showing strong positivity for both fibroblast activation protein <t>(FAP)</t> and <t>dipeptidylpeptidase-IV</t> <t>(DPP-IV).</t> IgG1, negative control. Scale bar, 50 μm.
Mouse Monoclonal Anti Fap F19, supplied by Becton Dickinson, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+fap/pmc02784039-100-3-20?v=Becton+Dickinson
Average 90 stars, based on 1 article reviews
mouse monoclonal anti-fap f19 - by Bioz Stars, 2026-07
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mouse fap duoset elisa  (Bio-Techne corporation)
93
Bio-Techne corporation mouse fap duoset elisa
Immunohistochemistry in low-grade myofibroblastic sarcoma, showing strong positivity for both fibroblast activation protein <t>(FAP)</t> and <t>dipeptidylpeptidase-IV</t> <t>(DPP-IV).</t> IgG1, negative control. Scale bar, 50 μm.
Mouse Fap Duoset Elisa, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+fap/bio-techne+corporation___dy8647-05?v=Bio-Techne+corporation
Average 93 stars, based on 1 article reviews
mouse fap duoset elisa - by Bioz Stars, 2026-07
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mouse fibroblast activation protein alpha/fap alexa fluor® 594-conjugated antibody  (Bio-Techne corporation)
90
Bio-Techne corporation mouse fibroblast activation protein alpha/fap alexa fluor® 594-conjugated antibody
Immunohistochemistry in low-grade myofibroblastic sarcoma, showing strong positivity for both fibroblast activation protein <t>(FAP)</t> and <t>dipeptidylpeptidase-IV</t> <t>(DPP-IV).</t> IgG1, negative control. Scale bar, 50 μm.
Mouse Fibroblast Activation Protein Alpha/Fap Alexa Fluor® 594 Conjugated Antibody, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+fap/bio-techne+corporation___fab9727t?v=Bio-Techne+corporation
Average 90 stars, based on 1 article reviews
mouse fibroblast activation protein alpha/fap alexa fluor® 594-conjugated antibody - by Bioz Stars, 2026-07
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Image Search Results


A Schematic diagram of fibrosis model establishment and treatment strategy in young or aged mice. B , C Young mouse BW changes ( B ) and survival curve ( C ) of control and BLM groups treated with IgG/ β LNP-FAPCAR 2.2, CD5/ β LNP-FAPCAR 2.2 (10 μg) and saline ( n = 10). The survival rate was analyzed using the log-rank (Mantel-Cox) test. D Lung coefficients (lung weight (mg)/BW (g)) ( n = 5,5,10,10,10,7). E tdTomato reporter gene expressed in T cells of spleen and lung at 24 h after the second CD5/ β LNP-FAPCAR 2.2 injection (Scar bar: 10 μm). F Flow cytometry plots for FAPCAR expression in CD3 + pulmonary T cells of BLM+Saline and CD5/ β LNP-FAPCAR 2.2 treatment groups and the ratio of FAPCAR expression to CD3 + pulmonary T cells ( n = 4). G Flow cytometry analysis of FAP + Pdgfra + fibroblasts in BLM+Saline and CD5/ β LNP-FAPCAR 2.2 treatment groups, ratio of FAP + Pdgfra + fibroblasts to all lung cells, and ratio of Pdgfra + fibroblasts (both FAP + and FAP — ) to all lung cells ( n = 4). H , I Representative micro-CT images and mean HU density ( H ), and lung air volume (mm 3 ) ( I ) computed according to CT results at postoperative 28 days ( n = 4,4,7,7,7,7). J Digital photos of lung tissue. ‘n’ means independent biological replications. The values are the means ± SDs. * P < 0.05. P -value determined by one-way ANOVA followed by Tukey’s multiple comparisons test ( D , F , H , I ) and two tailed unpaired Student’s t -test ( G ). (BW: body weight; HU: Hounsfield unit). Source data are provided as a Source Data file. Created in BioRender ( A , B ) .

Journal: Nature Communications

Article Title: Targeted immunotherapy rescues pulmonary fibrosis by reducing activated fibroblasts and regulating alveolar cell profile

doi: 10.1038/s41467-025-59093-7

Figure Lengend Snippet: A Schematic diagram of fibrosis model establishment and treatment strategy in young or aged mice. B , C Young mouse BW changes ( B ) and survival curve ( C ) of control and BLM groups treated with IgG/ β LNP-FAPCAR 2.2, CD5/ β LNP-FAPCAR 2.2 (10 μg) and saline ( n = 10). The survival rate was analyzed using the log-rank (Mantel-Cox) test. D Lung coefficients (lung weight (mg)/BW (g)) ( n = 5,5,10,10,10,7). E tdTomato reporter gene expressed in T cells of spleen and lung at 24 h after the second CD5/ β LNP-FAPCAR 2.2 injection (Scar bar: 10 μm). F Flow cytometry plots for FAPCAR expression in CD3 + pulmonary T cells of BLM+Saline and CD5/ β LNP-FAPCAR 2.2 treatment groups and the ratio of FAPCAR expression to CD3 + pulmonary T cells ( n = 4). G Flow cytometry analysis of FAP + Pdgfra + fibroblasts in BLM+Saline and CD5/ β LNP-FAPCAR 2.2 treatment groups, ratio of FAP + Pdgfra + fibroblasts to all lung cells, and ratio of Pdgfra + fibroblasts (both FAP + and FAP — ) to all lung cells ( n = 4). H , I Representative micro-CT images and mean HU density ( H ), and lung air volume (mm 3 ) ( I ) computed according to CT results at postoperative 28 days ( n = 4,4,7,7,7,7). J Digital photos of lung tissue. ‘n’ means independent biological replications. The values are the means ± SDs. * P < 0.05. P -value determined by one-way ANOVA followed by Tukey’s multiple comparisons test ( D , F , H , I ) and two tailed unpaired Student’s t -test ( G ). (BW: body weight; HU: Hounsfield unit). Source data are provided as a Source Data file. Created in BioRender ( A , B ) .

Article Snippet: FVS 700 (live/death dye, #564997, BD Bioscience, CA, USA), CD3e (#562600, BD Bioscience), CD8a (#557654, BD Bioscience), F4/80 (#565411, BD Bioscience), CD86 (#558703, BD Bioscience), CD163 (#12-1631-82, Thermo Fisher), FAP (#FAB9727G, R&D system) and Pdgfra (#12-1401-81, Thermo Fisher) were used in experiments.

Techniques: Control, Saline, Injection, Flow Cytometry, Expressing, Micro-CT, Two Tailed Test

Immunohistochemistry in low-grade myofibroblastic sarcoma, showing strong positivity for both fibroblast activation protein (FAP) and dipeptidylpeptidase-IV (DPP-IV). IgG1, negative control. Scale bar, 50 μm.

Journal: Histopathology

Article Title: Histogenesis-specific expression of fibroblast activation protein and dipeptidylpeptidase-IV in human bone and soft tissue tumours

doi: 10.1111/j.1365-2559.2009.03399.x

Figure Lengend Snippet: Immunohistochemistry in low-grade myofibroblastic sarcoma, showing strong positivity for both fibroblast activation protein (FAP) and dipeptidylpeptidase-IV (DPP-IV). IgG1, negative control. Scale bar, 50 μm.

Article Snippet: Primary antibodies were mouse monoclonal anti-FAP (clone F19), rat monoclonal anti-FAP (clone D8) and mouse monoclonal anti-DPP-IV (anti-CD26) (clone M-A261; Pharmingen, San Diego, CA, USA).

Techniques: Immunohistochemistry, Activation Assay, Negative Control

Immunohistochemistry of a fibroblastic area of an osteosarcoma. Fibroblast activation protein (FAP) and dipeptidylpeptidase-IV (DPP-IV) are strongly positive. Scale bar, 25 μm.

Journal: Histopathology

Article Title: Histogenesis-specific expression of fibroblast activation protein and dipeptidylpeptidase-IV in human bone and soft tissue tumours

doi: 10.1111/j.1365-2559.2009.03399.x

Figure Lengend Snippet: Immunohistochemistry of a fibroblastic area of an osteosarcoma. Fibroblast activation protein (FAP) and dipeptidylpeptidase-IV (DPP-IV) are strongly positive. Scale bar, 25 μm.

Article Snippet: Primary antibodies were mouse monoclonal anti-FAP (clone F19), rat monoclonal anti-FAP (clone D8) and mouse monoclonal anti-DPP-IV (anti-CD26) (clone M-A261; Pharmingen, San Diego, CA, USA).

Techniques: Immunohistochemistry, Activation Assay

Immunohistochemistry of an osteoblastic area of an osteosarcoma. Fibroblast activation protein (FAP) and dipeptidylpeptidase-IV (DPP-IV) are weakly positive in the osteoblastic area. Scale bar, 25 μm.

Journal: Histopathology

Article Title: Histogenesis-specific expression of fibroblast activation protein and dipeptidylpeptidase-IV in human bone and soft tissue tumours

doi: 10.1111/j.1365-2559.2009.03399.x

Figure Lengend Snippet: Immunohistochemistry of an osteoblastic area of an osteosarcoma. Fibroblast activation protein (FAP) and dipeptidylpeptidase-IV (DPP-IV) are weakly positive in the osteoblastic area. Scale bar, 25 μm.

Article Snippet: Primary antibodies were mouse monoclonal anti-FAP (clone F19), rat monoclonal anti-FAP (clone D8) and mouse monoclonal anti-DPP-IV (anti-CD26) (clone M-A261; Pharmingen, San Diego, CA, USA).

Techniques: Immunohistochemistry, Activation Assay

Immunohistochemistry in Ewing’s sarcoma. Tumour cells, small and round in shape, are negative for fibroblast activation protein (FAP) and dipeptidylpeptidase-IV (DPP-IV). Stromal cells in septal areas are positive for FAP and DPP-IV (marked with a star). Scale bar, 50 μm.

Journal: Histopathology

Article Title: Histogenesis-specific expression of fibroblast activation protein and dipeptidylpeptidase-IV in human bone and soft tissue tumours

doi: 10.1111/j.1365-2559.2009.03399.x

Figure Lengend Snippet: Immunohistochemistry in Ewing’s sarcoma. Tumour cells, small and round in shape, are negative for fibroblast activation protein (FAP) and dipeptidylpeptidase-IV (DPP-IV). Stromal cells in septal areas are positive for FAP and DPP-IV (marked with a star). Scale bar, 50 μm.

Article Snippet: Primary antibodies were mouse monoclonal anti-FAP (clone F19), rat monoclonal anti-FAP (clone D8) and mouse monoclonal anti-DPP-IV (anti-CD26) (clone M-A261; Pharmingen, San Diego, CA, USA).

Techniques: Immunohistochemistry, Activation Assay

Immunohistochemistry of a giant cell tumour. Fibroblast activation protein (FAP) is expressed in spindle-shaped fibroblastic cells, whereas dipeptidylpeptidase-IV (DPP-IV) is positive in giant cells. Scale bar, 25 μm.

Journal: Histopathology

Article Title: Histogenesis-specific expression of fibroblast activation protein and dipeptidylpeptidase-IV in human bone and soft tissue tumours

doi: 10.1111/j.1365-2559.2009.03399.x

Figure Lengend Snippet: Immunohistochemistry of a giant cell tumour. Fibroblast activation protein (FAP) is expressed in spindle-shaped fibroblastic cells, whereas dipeptidylpeptidase-IV (DPP-IV) is positive in giant cells. Scale bar, 25 μm.

Article Snippet: Primary antibodies were mouse monoclonal anti-FAP (clone F19), rat monoclonal anti-FAP (clone D8) and mouse monoclonal anti-DPP-IV (anti-CD26) (clone M-A261; Pharmingen, San Diego, CA, USA).

Techniques: Immunohistochemistry, Activation Assay